06:0 DIETHER PC

Not available outside of the UK & Ireland.

Application

06:0 Diether PC or 1,2-di-O-hexyl-sn-glycero-3-phosphocholine might be used:in bicelle media to measure the H—C one-bond residual dipolar couplings for trisaccharides, Lewis X (Lex) and Lewis A (Lea) methyl glycosides using nuclear magnetic resonance (NMR) residual dipolar couplingsto compose isotropically tumbling small bicelles, to study its size and morphology by 31P NMR and atomic force microscopy (AFM)in bicelle preparation for NMR studies

Biochem/physiol Actions

06:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Incorporating 06:0 Diether PC in bicelles results in bicelles similar to conventional phospholipid bicelles but with improved chemical stability.

General description

06:0 Diether PC (phosphocholine) is a glycerophospholipid having two hexane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Packaging

5 mL Clear Glass Sealed Ampule (999998P-10mg)