Application
08:0 Coenzyme A has been used as a substrate in microsomal ghrelin octanoyltransferase assay.
Biochem/physiol Actions
08:0 Coenzyme A acts as an intermediate in mitochondrial fatty acid β-oxidation. It hinders the activity of citrate synthase (CS) and glutamate dehydrogenase (GDH). Higher levels of octanoyl –CoA, due to reduced β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH), is observed in patients with MCADH deficiency (MCD).
General description
08:0 Coenzyme A, also referred as octanoyl Coenzyme A, is a medium-chain acyl CoA. It is a coenzyme A derivative of octanoic acid.
Packaging
5 mL Amber Glass Screw Cap Vial (870708P-5mg)
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