C8 LACTOSYL( BETA) CERAMIDE (D18:1/8:0)

Code: 860541P-5MG D2-231

Not available outside of the UK & Ireland.

Application

C8 Lactosyl(β) Ceramide (d18:1/8:0) is suitable for use as a substrate for endoglycoceramidase II. It is also suitable for use as a synthetic lipid standard for t...


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Your Price
$328.47 5MG
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Not available outside of the UK & Ireland.

Application

C8 Lactosyl(β) Ceramide (d18:1/8:0) is suitable for use as a substrate for endoglycoceramidase II. It is also suitable for use as a synthetic lipid standard for two-dimensional liquid chromatography−quadrupole time-of-flight mass spectrometry for lipid profiling and lipidomic analysis.

Biochem/physiol Actions

Lactosyl-β1-1′-N-octanoyl-D-erythro-sphingosine like other glycosphingolipids, stimulates caveolar endocytosis. C8-LacCer mediates clustering of β1-integrins and actin cytoskeleton reorganization in skin fibroblasts. High levels of lactosyl ceramide leads to decreased respiration leading to mitochondrial dysfunction.

General description

Lactosyl-ceramide is synthesized from complex glycosphingolipids by glucosylceramide synthase via caremide intermediate glucosylceramide.

Packaging

5 mL Amber Glass Screw Cap Vial (860541P-5mg)

formpowder
manufacturer/tradenameAvanti Polar Lipids 860541P
packagingpkg of 1 × 5 mg (860541P-5mg)
shipped indry ice
SMILES string[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
storage temp.−20°C
Cas Number384842-72-2
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