C11 TOPFLUOR (R) GLUCOSYL CERAMIDE

Not available outside of the UK & Ireland.

Application

C11 TopFluor^® Glucosyl Ceramide is suitable to use as a label in the GLM II model and as a component in the usual giant unilamellar vesicle (GUV) lipid mixture (GLM).

Biochem/physiol Actions

Glucosyl ceramide (GlcCer) plays a major role in the pathways ofglycosphingolipidmetabolism. It helps to modulate cell physiology. It acts as an intracellular messenger in cell maintenance and regulation.

General description

Glucosyl Ceramide (GlcCer)/cerebroside/galactosylceramide is a neutral, polar lipid. It can be ionized delicately in negative-andpositive-ionmodes. It is the simplest glycosphingolipids (GSLs), that is present abundantly in the mammalian tissues. GlcCer is produced through glycosylationof Cer with the help of GlcCersynthase(GCS) at the cytosolic leaflet ofGolgi apparatus.

Legal Information

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

Packaging

5 mL Amber Glass Screw Cap Vial (810267P-250ug)