18:1-06:0 NBD PA

Not available outside of the UK & Ireland.

Application

18:1-06:0 NBD PA may be used for study the effects of NBD-PA induced vesiculation on epidermal growth factor receptor (EGFR) endocytosis in mammalian cells and the co-localization of fluorescently-labeled poly(A)-specific ribonuclease (PARN) with the NBD-tagged PA that outlines the close proximity phospholipase D (PLD2) and PARN.

Biochem/physiol Actions

Phosphatidic acid (PA) is a bioactive lipid and a secondary messenger. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

General description

Phosphatidic acid (PA) is an amphipathic lipid containing a polar head group and two long hydrophobic acyl chains. PA is an anionic and a membrane structural lipid. It acts as a parent compound for more complex membrane phospholipids.

Packaging

5 mL Amber Glass Screw Cap Vial (810175P-10mg)