ADENOSINE 3 #, 5#-MONOP cyclique 1 pc x 5 umol

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Reversible: yes

Target K_i: 11 µM against protein kinase A

Product does not compete with ATP.

Cell permeable: yes

Primary TargetPKA

General description

A cell-permeable and reversible inhibitor of protein kinase A (K_i = 11 µM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.

Cell permeable inhibitor of protein kinase A (K_i = 11 µM). Resistant to hydrolysis by phosphodiesterases. Note: 5 µmol = 2.23 mg

Note: 5 µmol = 2.23 mg.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys.420, 336.Yokozaki, H., et al. 1992. Cancer Res.52, 2504. Butt, E., et al. 1990. FEBS Lett.263, 47.Dostmann, W.R., et al. 1990. J. Biol. Chem.265, 10484.Rothermel, J.D. 1988. Biochem. J. 251, 757.Eckstein, F. 1985. Annu. Rev. Biochem.54, 367.de Wit, R.J., et al. 1984. Eur. J. Biochem.142, 255.O′Brian, C.A., et al. 1982. Biochemistry21, 4371.

Packaging

5 µmol in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Warning

Toxicity: Standard Handling (A)