Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
NAMI-A is a ruthenium-based anticancer agent.
NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins. Nevertheless NAMI-A induces potent and selective cytotoxic effects in several leukemia cell lines. NAMI-A exhibits low toxicity for host tissues.
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