[Des-Tyr22] - saumon de calcitonine, >=97% (HPLC)

Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

Application

Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH). [Des-Tyr22]-Calcitonin salmon (Des-Tyr22-sCT) is an analogue of calcitonin with decreased in vitro adenylate cyclase activation activity and inhibitory activity for prolactin release from isolated rat pituitary cells.