Leflunomide, immunosuppresseur

Code: L5025-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases...


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Votre prix
$161.54 25MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases.

Biochem/physiol Actions

Immunosuppressive; inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is believed to inhibit dihydroorotate dehydrogenase (in the de novo pyrimidine synthesis pathway) as well as several protein tyrosine kinases.

Packaging

25, 100 mg in poly bottle

assay≥98% (TLC)
formpowder
Gene Informationhuman ... DHODH(1723)
InChI keyVHOGYURTWQBHIL-UHFFFAOYSA-N
InChI1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
mode of actionenzyme | inhibits
mp166.5 °C
Quality Level200
SMILES stringCc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F
solubilitymethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
storage temp.2-8°C
Cas Number75706-12-6
Hazard Class6.1
Un Number2811
Pack GroupIII
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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