2-Bromo-1-ethyl-pyridinium tetrafluoroborate, >=97.0% (T)

Not available outside of the UK & Ireland.

Application

2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:The synthesis of N-methylated peptides in solution and solid phase.The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.

General description

2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.

Other Notes

Coupling reagent for peptide synthesis; less racemization and faster reaction than with other reagents;e.g. BOP, PyBrOP, PyClU, BTFFH, CMBI

Packaging

5 g in poly bottle