N,N-Disuccinimidyl carbonate, purum, >=95.0% (NMR)

Code: 43720-25g D2-231

Not available outside of the UK & Ireland.

Application

N,N′-Disuccinimidyl carbonate (DSC) can be used to synthesize: Various carbamate derivatives from primary and sterically hindered secondary alc...


read more

Your Price
$434.39 25G

Not available outside of the UK & Ireland.

Application

N,N′-Disuccinimidyl carbonate (DSC) can be used to synthesize: Various carbamate derivatives from primary and sterically hindered secondary alcohols by alkoxycarbonylation. Active carbonate resins from 4-hydroxymethylpolystyrene and 4-hydroxymethyl-3-nitrobenzamido resins via hydroxy functional groups. Aza-glycinyl dipeptides, important intermediates for the preparation of various azapeptides.It may be also used:In the two-step preparation of 5-(6-(azidomethyl)nicotinamido)pentanoic acid, a copper-chelating picolyl azide derivative.To activate the hydroxyl group of the hapten, γ-hydroxyphenylbutazone (HPBZ) so that HPBZ can effectively bind with human serum albumin(HSA)-immunogen to form a hapten-protein conjugate.

Other Notes

Convenient reagent for preparing N-succinimidyl esters of N-protected amino acids and other acids; activated carbonate, e.g. synthesis of ureas and carbamates; coupling of ligands to proteins (via lysines).

application(s)peptide synthesis
assay≥95.0% (NMR)
formpowder
gradepurum
impurities~3% N-hydroxysuccinimide (NMR)
InChI keyPFYXSUNOLOJMDX-UHFFFAOYSA-N
InChI1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2
mp190 °C (dec.) (lit.)
Quality Level200
reaction suitabilityreaction type: Carbonylations
SMILES stringO=C1CCC(=O)N1OC(=O)ON2C(=O)CCC2=O
storage temp.−20°C
Cas Number74124-79-1
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN


GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.