POLYMÈRE TRUEGEL3D

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

FAST-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels.

Caution

Avoid frequent freeze-thaw cycles and store FAST-PVA polymer in small portions.

Components

TRUEPVAF contains FAST-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water.

Features and Benefits

Contains synthetic polymer (PVA) functionalized with maleimide groups for quick gelation Non degradable polymer

General description

PVA polymers are functionalized with thiol-reactive maleimide groups, which react rapidly with thiol groups of crosslinkers to form hydrogels in few seconds. The thiol-reactive maleimide groups are also compatible to conjugate polymers with bioactive factors. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. The buffers (pH7.2 and pH 5.5) are used to control pH and osmotic conditions to optimize time for gelation.