3-Chloropropiophenone, 98 %

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

3′-Chloropropiophenone can be used as a reactant to synthesize: (S)-3-chloro-1-phenylpropanol via bio-catalyzed asymmetric reduction method. 1-(3-Chlorophenyl)-1-phenyl-1-propanol by phenylation with diphenylzinc in the presence of dihydroxy bis(sulfonamide) ligand. (S)-Dapoxetine, a selective serotonin reuptake inhibitor.

General description

Influence of solvents and temperature on the yield and enantioselectivity of the phenylation of 3′-chloropropiophenone has been investigated.

Packaging

50 g in glass bottle