Formycine a; de Streptomyces kaniharaensis ; supérieure à =98% (HPLC)

Code: SMB00287-10MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Formycin A possess antitumor function, along with its antibacterial and antiviral activity.

Formycin A (FA) is a C-nucleoside that inhibits the ...


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$701.37 10MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Formycin A possess antitumor function, along with its antibacterial and antiviral activity.

Formycin A (FA) is a C-nucleoside that inhibits the E.coli enzyme purine nucleoside phosphorylase (PNP). FA was found to upsurge insulin release elevated by glucose, and was also shown to inhibit 5′-Methylthioadenosine/S-adenosylhomocysteine (MTA/AdoHcy) nucleosidase, an enzyme important in the recycling of methionine. Research has shown FA is an antiretroviral agent against HIV-1, targeting reverse transcription.

General description

Chemical structure: nucleoside

Formycin A is an adenosine analog, and is cytotoxic in nature. It acts as a substrate for the human enzymes human erythrocytic adenosine deaminase and adenosine kinase.

Other Notes

Store the product sealed at –20 °C. Under these conditions the product is stable for at least 4 years.

Keep container tightly closed in a dry and well-ventilated place.

Packaging

10MG

antibiotic activity spectrumviruses (Antiretroviral)
assay≥98% (HPLC)
biological sourceStreptomyces kaniharaensis
colorwhite to off-white
formpowder
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
InChI keyOIRDTQYFTABQOQ-KQYNXXCUSA-N
InChI1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
mode of actionenzyme | inhibits
Quality Level200
SMILES stringNc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
solubilityH2O: soluble 3 mg/mL, DMSO: soluble 1 mg/mL
storage condition(Keep container tightly closed in a dry and well-ventilated place.)
storage temp.−20°C
Cas Number6742-12-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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