Sel de sulfate de paromomycine, > = 98%( TLC)

Name: Sel de sulfate de paromomycine, > = 98%( TLC)
Brand: SIGMA-ALDRICH
SKU: P9297-25G
Price: 1020.42 USD

Code: P9297-25G D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo

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$1,020.42 25G

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Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth. It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line.
Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
General description
Chemical structure: aminoglycoside
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Packaging
1g,5g,25g

antibiotic activity spectrum parasites, Gram-positive bacteria, Gram-negative bacteria
assay ≥98% (TLC)
form powder
InChI key OYJABWUHUYVDMJ-UDXJMMFXSA-N
InChI 1S/C23H45N5O14.CH4/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;/h5-23,29-36H,1-4,24-28H2;1H4/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
mode of action protein synthesis | interferes
Quality Level 200
SMILES string O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@]2([H])[C@H](O[C@@]3([H])[C@H](O)[C@H](O[C@]4([H])[C@H](N)[C@@H](O)[C@H](O)[C@H](CN)O4)[C@@H](CO)O3)[C@@H](O)[C@H](N)C[C@@H]2N)[C@@H]1N.C

Fiche de données de sécurité
Safety Data Sheet for P9297-25G
Certificat d'analyse
Certificat d'analyse Sigma

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Cas Number 1263-89-4

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Sel de sulfate de paromomycine, > = 98%( TLC)

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antibiotic activity spectrum	parasites, Gram-positive bacteria, Gram-negative bacteria
assay	≥98% (TLC)
form	powder
InChI key	OYJABWUHUYVDMJ-UDXJMMFXSA-N
InChI	1S/C23H45N5O14.CH4/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;/h5-23,29-36H,1-4,24-28H2;1H4/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
mode of action	protein synthesis \| interferes
Quality Level	200
SMILES string	O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@]2([H])[C@H](O[C@@]3([H])[C@H](O)[C@H](O[C@]4([H])[C@H](N)[C@@H](O)[C@H](O)[C@H](CN)O4)[C@@H](CO)O3)[C@@H](O)[C@H](N)C[C@@H]2N)[C@@H]1N.C