2-Fluoro - 2 - déoxy - d-glucose, inhibiteur de glycosylation, analogique de glucose

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

2-Fluoro-2-deoxy-D-glucose is used as a tracer for rapid tumor detection. It is used as a glucose analog to study glucose uptake in mice with radiation and burn injuries. Oncology therapy studies use FDG in combination with PET (Positron Emission Topography)

Biochem/physiol Actions

Glucose analog that inhibits cellular glycosylation. Natural isotope-form of ¹⁸F-FDG that can be taken up by cells but does not undergo metabolic glycolysis.

General description

2-Fluoro-2-deoxy-D-glucose, also known as F-18 FDG, is non-toxic and a structural analog of glucose, significantly inhibiting glycosylation. As a glucose analog, uptake of 2-Fluoro-2-deoxy-D-glucose is rapid in brain and heart cells. 2-Fluoro-2-deoxy-D-glucose is a Natural isotope form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis.

Packaging

100 mg in glass bottle

25 mg in poly bottle