YM-202074 sesquifumarate salt hydrate, >=98% (HPLC)

Code: y1271-25mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

YM-202074 is a potent and selective allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist. It bound an allosteric site of rat mGluR1 w...


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$498.09 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

YM-202074 is a potent and selective allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist. It bound an allosteric site of rat mGluR1 with a Ki value of 4.8 nM. It also inhibited the mGluR1-mediated inositol phosphates production in rat cerebellar granule cells with an IC50 value of 8.6 nM, while showing selectivity over mGluR(2-7).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formpowder
InChI keyMCGFIZFYSARKON-RAMYONIISA-N
InChI1S/3C22H30N4O2S.2C4H4O4.H2O/c3*1-24(11-12-28-3)14-16-9-10-18-19(13-16)26-15-20(29-22(26)23-18)21(27)25(2)17-7-5-4-6-8-17;2*5-3(6)1-2-4(7)8;/h3*9-10,13,15,17H,4-8,11-12,14H2,1-3H3;2*1-2H,(H,5,6)(H,7,8);1H2/b;;;2*2-1+;
Quality Level100
SMILES stringO.OC(=O)C=CC(O)=O.OC(=O)C=CC(O)=O.COCCN(C)Cc1ccc2nc3sc(cn3c2c1)C(=O)N(C)C4CCCCC4.COCCN(C)Cc5ccc6nc7sc(cn7c6c5)C(=O)N(C)C8CCCCC8.COCCN(C)Cc9cccncsc(cncc9)C(=O)N(C)CCCCCC
solubilityH2O: >5 mg/mL, DMSO: >20 mg/mL
storage temp.room temp
Cas Number299900-84-8
Hazard Class6.1
Un Number2811
Pack Group3
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