LM11A - 31 dihydrochlorure,>=95% (HPLC)

Code: SML0664-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

LM11A-31 dihydrochloride has been used to study the effect of p75 neurotrophin receptor (p75 NTR) blockade, by non-peptide LM11A-31 ligand, on PC12 cell viability...


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Votre prix
$77.14 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

LM11A-31 dihydrochloride has been used to study the effect of p75 neurotrophin receptor (p75 NTR) blockade, by non-peptide LM11A-31 ligand, on PC12 cell viability.

Biochem/physiol Actions

LM11A-31 is a non-peptide ligand of the p75 neurotrophin receptor (p75NTR). LM11A-31 blocks pro-NGF induced cell death in neuronal cultures, and protects neuronal cells from the the cytotoxic effects of cisplatin or methotrexate. Oral administration of LM11A-31 promotes the survival of oligodendrocytes and myelinated axons in a mouse spinal cord injury model and improves function in both weight-bearing and non-weight bearing tests.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorcolorless to yellow
formoil
InChI keyLLIHJRRZJDEKLB-UHFFFAOYSA-N
InChI1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H
Quality Level100
SMILES stringCl.Cl.CCC(C)C(N)C(=O)NCCN1CCOCC1
storage conditiondesiccated
storage temp.2-8°C
Cas Number289475-77-0
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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