EVP4593, > = 98 %(HPLC)

Code: SML0579-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

EVP4593 is a high affinity partial antagonist of NF-KB pathway activation acting by inhibiting store-operated calcium (Ca2+) entry (SOC). I...


 En savoir plus

Votre prix
$199.24 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

EVP4593 is a high affinity partial antagonist of NF-KB pathway activation acting by inhibiting store-operated calcium (Ca2+) entry (SOC). It appears that EVP4593 targets heteromeric channels containing TRPC1 as one of the subunits in HD neurons. EVP4593 exhibits neuroprotective effects from glutamate toxicity in nanomolar concentrations.

Features and Benefits

This compound is featured on the Calcium Channels, Cytokine Receptors (Interleukin-1 Receptor/TIR Family) and Cytokine Receptors (Tumor Necrosis Receptor Family) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Air sensitive

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyIBAKVEUZKHOWNG-UHFFFAOYSA-N
InChI1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14-15H,12-13,23H2,(H,24,25,26)
Quality Level100
SMILES stringNC1=CC(C(NCCC2=CC=C(OC3=CC=CC=C3)C=C2)=NC=N4)=C4C=C1
solubilityDMSO: 15 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number545380-34-5
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN
GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.