Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Tirapazamine has been used to evaluate its cytotoxic effect on U-251 MG (glioblastoma cell line) cell viability.
Biochem/physiol Actions
Under hypoxic conditions, tirapazamine is a potent cytotoxic agent that induces apoptosis by inducing breaks in single and double stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin.
Packaging
10, 50 mg in glass bottle
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :