SB - 590885, > = 98 %(HPLC)

Name: SB - 590885, > = 98 %(HPLC)
Brand: SIGMA-ALDRICH
SKU: SML0501-25MG
Price: 481.94 USD

Code: SML0501-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SB-590885 has been used as a component of a mixture to maintain naive human pluripotent stem cells (PSCs).It has also been used as B-Raf (BRAF) inhibitor to study...

Votre prix

$481.94 25MG

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PRÉSENTATION
SPÉCIFICATIONS
DOCUMENTS
ATTRIBUTS

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SB-590885 has been used as a component of a mixture to maintain naive human pluripotent stem cells (PSCs).It has also been used as B-Raf (BRAF) inhibitor to study its effects on lung adenocarcinoma cell lines.

Biochem/physiol Actions

SB-590885 is a potent and selective ATP competitive inhibitor of B-Raf kinase with Kd = 300 pM for B-Raf, and >1000-fold selectivity over a panel of 22 commonly studied cellular kinases

Features and Benefits

This compound is featured on the MAPKKKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	MLSAQOINCGAULQ-QLTSDVKISA-N
InChI	1S/C27H27N5O2/c1-32(2)15-16-34-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)31-33/h3-5,7-9,11-14,17,33H,6,10,15-16H2,1-2H3,(H,29,30)/b31-24-
Quality Level	100
SMILES string	CN(C)CCOc1ccc(cc1)-c2nc(-c3ccc4c(CCC4=NO)c3)c([nH]2)-c5ccncc5
solubility	DMSO: 2 mg/mL (clear solution, warmed)
storage temp.	2-8°C

Safety Data Sheet for SML0501-25MG
Certificat d'analyse Sigma

Cas Number

405554-55-4

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

SB - 590885, > = 98 %(HPLC)

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