NCTT-956, >=97% (NMR)

Code: sml0499-5mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity, with an IC50 of 800 nM, no activity against 5-LO and gre...


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$128.56 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity, with an IC50 of 800 nM, no activity against 5-LO and greater than 25-fold selectivity over 15-LO. Specific inhibition of 12-LO by NCTT-956 in platelets blocks PKC activation, aggregation, granule secretion and αIIbB3 activation.

Packaging

5, 25 mg in glass bottle

assay≥97% (NMR)
colorlight orange to dark orange
formpowder
InChI keyDEXNORPUTBBNSC-UHFFFAOYSA-N
InChI1S/C17H15N3O4S/c1-2-14(21)19-15(13-6-4-8-25-13)11-9-12(20(23)24)10-5-3-7-18-16(10)17(11)22/h3-9,15,22H,2H2,1H3,(H,19,21)
Quality Level100
SMILES stringCCC(=O)NC(c1cccs1)c2cc([N+]([O-])=O)c3cccnc3c2O
solubilityDMSO: 5 mg/mL (clear solution)
storage temp.2-8°C
Cas Number438575-88-3
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