Qc1, >=98% (HPLC)

Code: sml0481-5mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Qc1 is a reversible inhibitor of threonine dehydroxygenase (TDH). The IC50 value for inhibition of TDH by Qc1 is 500 nM, with no detectable...


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$130.45 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Qc1 is a reversible inhibitor of threonine dehydroxygenase (TDH). The IC50 value for inhibition of TDH by Qc1 is 500 nM, with no detectable inhibition of other dehydroxygenase enzymes at concentrations up to 10 mM. Qc1 induces arrest and autophagy of mouse ES cells with an EC50 of 3 mM.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyIFNVTSPDMUUAFY-UHFFFAOYSA-N
InChI1S/C23H16F3N3O2S/c24-23(25,26)16-7-4-8-17(12-16)29-21(31)18-10-9-15(11-19(18)28-22(29)32)20(30)27-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,27,30)(H,28,32)
Quality Level100
SMILES stringFC(F)(F)c1cccc(c1)N2C(=S)Nc3cc(ccc3C2=O)C(=O)NCc4ccccc4
solubilityDMSO: 5 mg/mL (clear solution, warmed)
storage temp.2-8°C
Cas Number403718-45-6
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