Dorzolamide, >=98% (HPLC)

Code: sml0468-50mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vit...


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$438.86 50MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... CA2(760)
InChI keyIAVUPMFITXYVAF-XPUUQOCRSA-N
InChI1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1
optical activity[α]/D -25 to -35°, c = 1 in methanol
Quality Level100
SMILES stringCCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
solubilityDMSO: 5 mg/mL (clear solution, warmed)
storage temp.room temp
Cas Number120279-96-1
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