Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Nitisinone has been used:to induce liver injuryto treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenasein supplemented water to block the accumulation of toxic metabolites in human hepatocyte engrafted miceto study its effect on bacterial pyomelanin production
Biochem/physiol Actions
Nitisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase). Nitisinone is used in the treatment of hereditary tyrosinemia type 1, where it blocks the degradation of tyrosine into harmful substances.
Packaging
10, 50 mg in glass bottle
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :