ZL006, > = 98 %(HPLC)

Code: SML0146-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ZL006, a novel neuroprotectant, is also called as 5-(3, 5-dichloro-2-hydroxybenzylamino)-2-hydroxybenzoic acid. It has the ability to block the intera...


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Votre prix
$433.48 25MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ZL006, a novel neuroprotectant, is also called as 5-(3, 5-dichloro-2-hydroxybenzylamino)-2-hydroxybenzoic acid. It has the ability to block the interaction of neuronal nitric oxide synthase (nNOS)/postsynaptic density protein-95 (PSD-95) in co-immunoprecipitation assays of extracts from glutamate or cultured neurons and cortical brain, stimulated by ischemia.

ZL006 inhibits the ischemia-induced interaction of nNOS with postsynaptic density protein-95 (PSD-95), preventing glutamate-induced excitotoxicity and cerebral ischemic damage. It does not inhibit nNOS itself. ZL006 is brain penetrant, and has been tested in both rat and mouse models of stroke.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
InChI keyRTEYSQSXRFVKTJ-UHFFFAOYSA-N
InChI1S/C14H11Cl2NO4/c15-8-3-7(13(19)11(16)4-8)6-17-9-1-2-10(14(20)21)12(18)5-9/h1-5,17-19H,6H2,(H,20,21)
Quality Level100
SMILES stringOC1=C(Cl)C=C(Cl)C=C1CNC(C=C2)=CC(O)=C2C(O)=O
solubilityDMSO: ≥5 mg/mL (warmed to 60° C)
storage temp.2-8°C
Cas Number1181226-02-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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