Montelukast sodium hydrate, >=98% (HPLC)

Code: sml0101-50mg D2-231

Not available outside of the UK & Ireland.

Application

Montelukast sodium hydrate has been used as a positive control drug to study the protective effects of Gumiganghwal-tang aqueous extract (GGTA) against airway inf...


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Your Price
$580.21 50MG
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Not available outside of the UK & Ireland.

Application

Montelukast sodium hydrate has been used as a positive control drug to study the protective effects of Gumiganghwal-tang aqueous extract (GGTA) against airway inflammation and pulmonary fibrosis.

Biochem/physiol Actions

Montelukast sodium hydrate is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is a subtype specific CysLT1 receptor antagonist.

Features and Benefits

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
InChI keyQAXHQHBRRJHZHL-ZPQUALOVSA-M
InChI1S/C35H36ClNO3S.Na.H2O/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);;1H2/q;+1;/p-1/b15-10+;;/t32-;;/m1../s1
optical activity[α]/D +90 to +106° in methanol (c=1)
originatorMerck & Co., Inc., Kenilworth, NJ, U.S.
Quality Level100
SMILES stringO.[Na+].CC(C)(O)c1ccccc1CC[C@@H](SCC2(CC2)CC([O-])=O)c3cccc(C=Cc4ccc5ccc(Cl)cc5n4)c3
solubilityDMSO: ≥8 mg/mL at 60 °C
storage conditiondesiccated
storage temp.2-8°C
Cas Number151767-02-1
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