Conessine, >= 97%( HPLC )

Code: SML0095-50MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5.37 and 24.5 nM for hu...


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$191.16 50MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5.37 and 24.5 nM for human and rat receptors, respectively). Conessine is 1860-fold selective for H3 over H4 and does not bind to H1 or H2 receptors. The molecule also binds to the human α2C4 adrenergic receptor (pKi = 7.98).

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

Conessine is a steroidal alkaloid. It has anti-malarial properties, thus, conessine has been used in treatment of malaria.

Packaging

10, 50 mg in glass bottle

assay≥97% (HPLC)
colorwhite to tan
formpowder
InChI keyGPLGAQQQNWMVMM-MYAJQUOBSA-N
InChI1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
originatorAbbott
Quality Level100
SMILES stringC[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23CN1C)N(C)C
solubilityethanol: ≥2 mg/mL
storage temp.2-8°C
Cas Number546-06-5
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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