SYUIQ - 5 ,>= 98 %(HPLC)

Code: S5826-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SYUIQ-5 may be used in autophagy and DNA damage-inducing cell signaling studies.

Biochem/physiol Actions

SYUIQ-5 is a Cryptolepine de...


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Votre prix
$328.47 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SYUIQ-5 may be used in autophagy and DNA damage-inducing cell signaling studies.

Biochem/physiol Actions

SYUIQ-5 is a Cryptolepine derivative, which induces and stabilizes G-quadruplexes. In CNE2 and HeLa cancer cells SYUIQ-5 triggers rapid and potent telomere DNA damage through TRF2 delocalization from telomeres and induces cell death by autophagy. In low concentration the compound caused senescence and telomere shortening. It is a potent cytotoxic agent.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloryellow
formpowder
InChI keyCTDCVGDSVHUYMA-UHFFFAOYSA-N
InChI1S/C20H22N4/c1-24(2)13-7-12-21-18-14-8-3-5-10-16(14)22-19-15-9-4-6-11-17(15)23-20(18)19/h3-6,8-11,23H,7,12-13H2,1-2H3,(H,21,22)
Quality Level100
SMILES stringCN(C)CCCNc1c2ccccc2nc3c4ccccc4[nH]c13
solubilityDMSO: ≥20 mg/mL
storage temp.2-8°C
Cas Number188630-47-9
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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