Chlorure de SB - 204070, solide, >= 97% (HPLC)

Code: S3313-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.

Biochem/physiol Actions

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Votre prix
$768.68 5MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.

Biochem/physiol Actions

Selective 5-HT4 serotonin receptor antagonist.

SB-204070 is a highly potent and specific antagonist of 4-HT4 receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.

Legal Information

Manufactured and sold under exclusive license from GlaxoSmithKline Pharmaceuticals

Packaging

5, 25 mg in glass bottle

assay≥97% (HPLC)
formsolid
Gene Informationhuman ... HTR4(3360)
InChI keyYEQGKAOSYSXEPU-UHFFFAOYSA-N
InChI1S/C19H27ClN2O4.ClH/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18;/h11,13H,2-10,12,21H2,1H3;1H
mp243-245 °C (lit.)
Quality Level100
SMILES stringCl[H].CCCCN1CCC(CC1)COC(=O)c2cc(Cl)c(N)c3OCCOc23
solubilityH2O: 20 mg/mL (with heating)
Cas Number148702-58-3
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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