RepSox, >= 98%( HPLC )

Code: R0158-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

RepSox has been used as an inhibitor of autophosphorylation of the transforming growth factor β type I receptor kinase (ALK5). It has also been used as a basal me...


 En savoir plus

Votre prix
$201.93 5MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

RepSox has been used as an inhibitor of autophosphorylation of the transforming growth factor β type I receptor kinase (ALK5). It has also been used as a basal media component for culturing human Pluripotent stem cells.

Biochem/physiol Actions

RepSox inhibits osteoclast differentiation, resorption in bone tissues and ovariectomy (OVX)‐induced osteoporosis (OP) through repression of the SMAD family member 3 (Smad3) and c-Jun N-terminal kinase (JNK) pathway/ activator protein 1 (AP-1) pathways.

RepSox Inhibits TGF-beta receptor signaling. Retroviral transduction of Sox2, Oct4, and Klf4 genes results in direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
formsolid
InChI keyLBPKYPYHDKKRFS-UHFFFAOYSA-N
InChI1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
Quality Level100
SMILES stringCc1cccc(n1)-c2n[nH]cc2-c3ccc4ncccc4n3
solubilityDMSO: >20 mg/mL
storage temp.2-8°C
Cas Number446859-33-2
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN
GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.