1,2-Dipalmitoylphosphatidylinositol 3,4-diphosphate sodium salt, >=98%, solid

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Diphosphorylated phosphatidylinositol that may be hydrolyzed by PI-specific phospholipase C to generate IP₃ and DAG.

Preparation Note

The product is soluble in aqueous detergent solutions. It forms a clear solution at 8 mg/ml in 50 mM HEPES buffer, pH 7.0, containing 5 mM EDTA and 16 mg/ml sodium deoxycholate. It is also soluble in a 3:2:1 mixture of chloroform:methanol:water at 10 mg/ml and will form an opaque suspension at 1 mg/ml in phosphate-buffered saline (PBS), pH 7.2. Aqueous solutions remain active for less than 24 hours.