Sel de maléate de Pyrilamine,

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Pyrilamine maleate salt has been used:to treat Cassiopea sp. as H₁ receptor antagonistto intraperitoneally inject mice to prevent the release of endogenous histaminein membrane binding assay to determine the K_i values and in the comparative inhibitory concentration (IC₅₀) studies by whole-cell patch clamp technique

Biochem/physiol Actions

Pyrilamine maleate is a H1 histamine receptor antagonist. Pyrilamine maleate induces sleep in vertebrates. In Cassiopea, it induces concentration dependent dormancy.

Features and Benefits

This compound was developed by Watson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25, 100 g in glass bottle