Penitrem a, > = 95 %(HPLC et TLC)

Name: Penitrem a, > = 95 %(HPLC et TLC)
Brand: SIGMA-ALDRICH
SKU: P3053-5MG
Price: 1413.51 USD

Code: P3053-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Penitrem A has been used as Ca²⁺-Activated K⁺ (BK) channel blocker to study its effect on BK current in bag cell neurons.

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$1,413.51 5MG

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Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Penitrem A has been used as Ca²⁺-Activated K⁺ (BK) channel blocker to study its effect on BK current in bag cell neurons.
Biochem/physiol Actions
Penitrem A intoxication causes ataxia, polypnea, and sustained tremors and may lead to seizures and death. Penitrem A affects the central and peripheral nervous system. It impairs the GABAergic neurotransmission in the cerebellum.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes
Originally isolated from Penicillium palitans
Packaging
1, 5 mg in glass bottle

assay ≥95% (HPLC and TLC)
form powder
InChI key JDUWHZOLEDOQSR-JKPSMKLGSA-N
InChI 1S/C37H44ClNO6/c1-15(2)28-27(40)31-37(45-31)23(43-28)9-10-33(6)34(7)18(8-11-35(33,37)41)29-25-24-21(39-30(25)34)14-20(38)17-12-16(3)19-13-22(32(4,5)44-29)36(19,42)26(17)24/h14,18-19,22-23,27-29,31,39-42H,1,3,8-13H2,2,4-7H3/t18-,19+,22+,23-,27-,28+,29-,31+,33+,34+,35-,36+,37-/m0/s1
Quality Level 200
SMILES string [H][C@]12CC[C@@]3(C)[C@@](O)(CC[C@@]4([H])[C@]5([H])OC(C)(C)[C@@]6([H])C[C@]7([H])C(=C)Cc8c(Cl)cc9[nH]c(c5c9c8[C@]67O)[C@]34C)[C@]1O[C@]([H])[C@@H](O)[C@H](O2)C(C)=C
storage temp. 2-8°C

Fiche de données de sécurité
Safety Data Sheet for P3053-5MG
Certificat d'analyse
Certificat d'analyse Sigma

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Cas Number 12627-35-9
Hazard Class 6.1
Un Number 2811
Pack Group 2

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Penitrem a, > = 95 %(HPLC et TLC)

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assay	≥95% (HPLC and TLC)
form	powder
InChI key	JDUWHZOLEDOQSR-JKPSMKLGSA-N
InChI	1S/C37H44ClNO6/c1-15(2)28-27(40)31-37(45-31)23(43-28)9-10-33(6)34(7)18(8-11-35(33,37)41)29-25-24-21(39-30(25)34)14-20(38)17-12-16(3)19-13-22(32(4,5)44-29)36(19,42)26(17)24/h14,18-19,22-23,27-29,31,39-42H,1,3,8-13H2,2,4-7H3/t18-,19+,22+,23-,27-,28+,29-,31+,33+,34+,35-,36+,37-/m0/s1
Quality Level	200
SMILES string	[H][C@]12CC[C@@]3(C)[C@@](O)(CC[C@@]4([H])[C@]5([H])OC(C)(C)[C@@]6([H])C[C@]7([H])C(=C)Cc8c(Cl)cc9[nH]c(c5c9c8[C@]67O)[C@]34C)[C@]1O[C@]([H])[C@@H](O)[C@H](O2)C(C)=C
storage temp.	2-8°C