PS48 ,> = 98 %( HPLC)

Code: P0022-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48...


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$208.66 5MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formpowder
InChI keyLLJYFDRQFPQGNY-QINSGFPZSA-N
InChI1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
Quality Level100
SMILES stringOC(=O)C=C(CCc1ccc(Cl)cc1)c2ccccc2
solubilityDMSO: >20 mg/mL
storage conditionprotect from light
storage temp.2-8°C
Cas Number1180676-32-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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