NH125,> = 98 %( HPLC), solide

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

IC₅₀ = 60 nM for eEF-2 kinase vs protein kinase C (IC₅₀= 7.5 µM), protein kinase A (IC₅₀= 80 µM), and calmodulin-dependent kinase II IC₅₀ > 100 µM).

Biochem/physiol Actions

NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K).

NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase.

Packaging

Packaged under nitrogen.

5, 25 mg in glass bottle