Isoqx hydrate de sel désinfecté, > = 98 %( HPLC), solide lyophilisé

Name: Isoqx hydrate de sel désinfecté, > = 98 %( HPLC), solide lyophilisé
Brand: SIGMA-ALDRICH
SKU: N183-5MG
Price: 371.55 USD

Code: N183-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

NBQX disodium salt hydrate has been used:in N-methyl-D-aspartate receptor (NMDAR) kinetic studiesas an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic ac...

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$371.55 5MG

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ATTRIBUTS

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

NBQX disodium salt hydrate has been used:in N-methyl-D-aspartate receptor (NMDAR) kinetic studiesas an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist for the electrophysiological studies cultured neuronsin the extracellular solution for current/voltage (I/V) relationship and rectification index experiments in excitatory postsynaptic currents (EPSCs) mediated by NMDA receptors (EPSC_NMDAR)

Biochem/physiol Actions

NBQX disodium salt hydrate is a neuroprotective AMPA/kainate glutamate receptor antagonist.

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

assay	≥98% (HPLC)
color	, brown to dark red-brown
form	lyophilized powder
Gene Information	human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901)
InChI key	LQSCHRKYVVVUFA-UHFFFAOYSA-L
InChI	1S/C12H8N4O6S.2Na.H2O/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6;;;/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22);;;1H2/q;2*+1;/p-2
Quality Level	100
SMILES string	O.[Na+].[Na+].NS(=O)(=O)c1cccc2c1c(cc3nc([O-])c([O-])nc23)[N+]([O-])=O
solubility	H₂O: >10 mg/mL
storage condition	desiccated
storage temp.	2-8°C

Safety Data Sheet for N183-5MG
Certificat d'analyse Sigma

Cas Number

118876-58-7

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Isoqx hydrate de sel désinfecté, > = 98 %( HPLC), solide lyophilisé

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