Nimodipine, solide

Code: N149-500MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Nimodipine has been used:as a L-type calcium channel (LTCC) inhibitor, to evaluate its neuroprotective activity in the vibrosectionsas a standard, in the enantios...


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Votre prix
$485.98 500MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Nimodipine has been used:as a L-type calcium channel (LTCC) inhibitor, to evaluate its neuroprotective activity in the vibrosectionsas a standard, in the enantioseparation of chiral drugs by high performance liquid chromatography (HPLC)in the pharmacological studies for the measurement of spine voltage escape

Biochem/physiol Actions

Nimodipine is a potent L-type Ca2+ channel antagonist.

Nimodipine enhances the survival of dopaminergic substantia nigra neurons.

Caution

Photosensitive

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N149.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

100, 500 mg in poly bottle

assay≥98% (HPLC)
coloroff-white to yellow
formpowder
Gene Informationhuman ... ADORA3(140), CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNG1(786), NR3C2(4306)rat ... Adora1(29290), Adora2a(25369)
InChI keyUIAGMCDKSXEBJQ-UHFFFAOYSA-N
InChI1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
originatorBayer
Quality Level200
SMILES stringCOCCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC(C)C
solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: insoluble, methanol: 62.5 mg/mL, H2O: insoluble
Cas Number66085-59-4
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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