MME 1754 hydrate, >= 98%( HPLC ), solide

Code: M6316-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

MRS 1754 hydrate has been used as an adenosine receptor A2B (RA2B) antagonist: to study its effects on endothelial nitric oxide synthase (eNOS) phosphorylation in...


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Votre prix
$309.63 5MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

MRS 1754 hydrate has been used as an adenosine receptor A2B (RA2B) antagonist: to study its effects on endothelial nitric oxide synthase (eNOS) phosphorylation induced by short-term acetate stimulation in human umbilical vein endothelial cells (HUVECs) blastema formation in zebrafish to serve as a positive control in the anti-sickling assay and to study the role of RA2B in the same

Biochem/physiol Actions

MRS 1754 hydrate is a potent A2B adenosine receptor antagonist.

MRS 1754 hydrate is a p-cyanoanilide xanthine derivative. It might act as a potential anti-asthmatic drug.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold under license from Adenosine Therapeutics LLC.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloroff-white
formsolid
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora2b(29316)
InChI keyZACJDWOPQROWIK-UHFFFAOYSA-N
InChI1S/C26H26N6O4.H2O/c1-3-13-31-24-22(25(34)32(14-4-2)26(31)35)29-23(30-24)18-7-11-20(12-8-18)36-16-21(33)28-19-9-5-17(15-27)6-10-19;/h5-12H,3-4,13-14,16H2,1-2H3,(H,28,33)(H,29,30);1H2
Quality Level100
SMILES stringO.CCCN1C(=O)N(CCC)c2[nH]c(nc2C1=O)-c3ccc(OCC(=O)Nc4ccc(cc4)C#N)cc3
solubilityDMSO: soluble >10 mg/mL
storage temp.room temp
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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