Hydrate de dihydrochlorure de Mibefradil, >=98% (HPLC), poudre

Code: M5441-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Mibefradil has been used as a T-type calcium channel blocker in various cells. It has also been used to reduce apoptosis of retinal ganglion cells (RGC) in EphB2-...


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Votre prix
$922.15 25MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Mibefradil has been used as a T-type calcium channel blocker in various cells. It has also been used to reduce apoptosis of retinal ganglion cells (RGC) in EphB2-Fc.

Biochem/physiol Actions

Ro 40-5967 is a T-type Ca2+ channel blocker; antihypertensive.

Mibefradil is a tetralol derivative and nondihydropyridine calcium channel blocker. It blocks long-type (L-type) calcium channels. It blocks mildly the Purkinje-type (P-type) calcium channels in Purkinje neurons.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
InChI keyIZSWBBGKLWFDOC-YKXHUFBBSA-N
InChI1S/C29H38FN3O3.2ClH.H2O/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;;;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);2*1H;1H2/t28-,29-;;;/m0.../s1
originatorRoche
Quality Level100
SMILES stringO.Cl.Cl.COCC(=O)O[C@]3(CCN(C)CCCc1nc2ccccc2[nH]1)CCc4cc(F)ccc4[C@@H]3C(C)C
solubilityabsolute ethanol: insoluble, H2O: soluble >20 mg/mL
storage conditiondesiccated
Cas Number116666-63-8
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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