Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor:to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylationsto analyze its effects on the growth of Arabidopsis thaliana seedlingsto study its effects on craniofacial chondrocyte maturation
Biochem/physiol Actions
MB-3 is a Gcn5 HAT (Histone Acetyltransferase) inhibitor; anti-inflammatory, anti-carcinogenic.
MB-3 can modify the gene expression in murine embryonic stem cells as well as yeast. It hinders the acetyltransferase activity of general control non-repressible 5 (GCN5) by binding to acetyl CoA pocket present in GCN5.
Features and Benefits
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Packaging
5, 25 mg in glass bottle
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