Sel de citrate de méthyllycaconitine, à partir de graines de brownii de Delphinium, >=96% (HPLC)

Name: Sel de citrate de méthyllycaconitine, à partir de graines de brownii de Delphinium, >=96% (HPLC)
Brand: SIGMA-ALDRICH
SKU: M168-25MG
Price: 555.98 USD

Code: M168-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Methyllycaconitine citrate salt has been used as an α7 nicotinic acetylcholine receptor (α7 nAChR) antagonist:to study its effects on inflammatory response in rat...

AJOUTER

Votre prix

$555.98 25MG

DEMANDER

DEMANDER UN DEVIS

PRÉSENTATION
SPÉCIFICATIONS
DOCUMENTS
ATTRIBUTS

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Methyllycaconitine citrate salt has been used as an α7 nicotinic acetylcholine receptor (α7 nAChR) antagonist:to study its effects on inflammatory response in rats post nicotine treatmentto block the activity of galantamineto study its effects on the hepatic branch of the vagus nerve (hVNS) in rats

Biochem/physiol Actions

Methyllycaconitine (MLA) is an α7 nicotinic acetylcholine receptor (α7 nAChR) antagonist. It is a norditerpenoid alkaloid synthesized by several species of Delphinium. MLA binds to the binding site of neuronal α-bungarotoxin. Low doses of MLA are associated with improvement of cognition in animals.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay	≥96% (HPLC)
biological source	Delphinium brownii seeds
color	white
InChI key	INBLZNJHDLEWPS-DDIMIZGISA-N
InChI	1S/C37H50N2O10.C6H8O7/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t19-,21+,22+,24-,25-,27+,28-,29+,30-,33?,34-,35+,36-,37+;/m0./s1
Quality Level	100
SMILES string	O=C(OC[C@]12[C@@]([C@]3([C@H](CC1)OC)[C@@H]4N(C2)CC)([H])[C@@H]([C@]4(O)[C@]5(O)[C@]6([H])[C@@]3([H])C[C@@]([C@H](C5)OC)([H])[C@@H]6OC)OC)C7=CC=CC=C7N8C([C@@H](C)CC8=O)=O.OC(CC(CC(O)=O)(C(O)=O)O)=O
solubility	H₂O: 42 mg/mL
storage temp.	−20°C

Safety Data Sheet for M168-25MG
Certificat d'analyse Sigma

Cas Number

21019-30-7

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Sel de citrate de méthyllycaconitine, à partir de graines de brownii de Delphinium, >=96% (HPLC)

À PROPOS DE NOUS

INFORMATIONS

FORMULAIRES

NOUS APPELER