Jervine,> = 98 %( HPLC), poudre

Name: Jervine,> = 98 %( HPLC), poudre
Brand: SIGMA-ALDRICH
SKU: J4145-1MG
Price: 203.28 USD

Code: J4145-1MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Jervine is a sonic hedgehog (Shh) pathway inhibitor.

Jervine is a potent teratogenic agent. It can induce apoptosis in leukemia cells and MUTZ-1...

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$203.28 1MG

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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Jervine is a sonic hedgehog (Shh) pathway inhibitor.

Jervine is a potent teratogenic agent. It can induce apoptosis in leukemia cells and MUTZ-1 cells. Jervine is an inhibitor of Hedgehog signaling. It exhibits anti-cancer effects on human prostate cancer. It also increases the chemosensitivity of breast cancer cells to doxorubicin treatment. Jervine may be used for treating hypertension and heart disease.

General description

Jervine is a steroid alkaloid present in Veratrum californicum.

Packaging

1 mg in glass bottle

assay	≥98% (HPLC)
form	powder
Gene Information	human ... EBP(10682)
InChI key	CLEXYFLHGFJONT-DNMILWOZSA-N
InChI	1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
Quality Level	100
SMILES string	[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
solubility	methanol: >2 mg/mL, H₂O: insoluble
storage temp.	−20°C

Safety Data Sheet for J4145-1MG
Certificat d'analyse Sigma

Cas Number	469-59-0
Hazard Class	6.1
Un Number	2811
Pack Group	3

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Jervine,> = 98 %( HPLC), poudre

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