4-Hydroxytamoxifen, > = 70 % Z isomère( reste principalement isomère e)

Code: H6278-10MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Metabolite of the chemotherapeutic drug tamoxifen, exhibiting more potent estrogen agonist/antagonist activity than the parent drug. Also active as in...


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$113.48 10MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Metabolite of the chemotherapeutic drug tamoxifen, exhibiting more potent estrogen agonist/antagonist activity than the parent drug. Also active as intra-membranous inhibitor of lipid peroxidation.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

50 mg in glass bottle

10 mg in poly bottle

antibiotic activity spectrumneoplastics
assay≥98% (HPLC)
formpowder
Gene Informationhuman ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)rat ... Ar(24208), Esr1(24890), Esr2(25149)
InChI keyZJLDABGSDWXVGE-BDSXMVAQSA-N
InChI1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-
mode of actionenzyme | inhibits
originatorAstraZeneca
Quality Level300
SMILES stringCCC(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CCC(c4ccccc4)=C(c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6
solubilitymethanol: 10 mg/mL, ethanol: 20 mg/mL (with heating)
storage conditionprotect from light, desiccated
storage temp.2-8°C
Cas Number68392-35-8
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