Hyperforin, >=85% (HPLC), 0.25 mg/mL in methanol, solution

Code: h5160-250ug D2-231

Not available outside of the UK & Ireland.

Application

Hyperforin may be used:as a reference standard for calibration curve generation in high-perfornamce liquid chromatography (HPLC) analysisto test its cytotoxic eff...


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$324.43 250UG
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Not available outside of the UK & Ireland.

Application

Hyperforin may be used:as a reference standard for calibration curve generation in high-perfornamce liquid chromatography (HPLC) analysisto test its cytotoxic effect and apoptosis induction in mouse embryonic cellsas a pregnane X receptor (PXR) in porcine brain capillary endothelial cells for transport assay

Biochem/physiol Actions

Hyperforin is an active antidepressant and an inhibitor of cytochrome P450 3A4 (CYP3A). It elicits antioxidant and antibacterial activity. Hyperforin is also embryotoxic and inhibits tumor proliferation. It effectively inhibits dopamine, serotonin and norepinephrine.

General description

Hyperforin is a phloroglucinol component of St. John′s wort and a pregnane X receptor ligand.

assay≥85% (HPLC)
concentration0.84 mg/mL in methanol
formsolution
InChI keyIWBJJCOKGLUQIZ-HQKKAZOISA-N
InChI1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,38H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1
Quality Level100
SMILES stringCC(C)C(=O)[C@@]12C(O)=C(CC=C(C)C)C(=O)[C@@](CC=C(/C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O
storage temp.−20°C
Cas Number11079-53-1
This product has met the following criteria to qualify for the following awards:



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