cis-5,8,11,14,17 - sel acide sodium eicosapentaénique, >=99% (GC capillaire)

Name: cis-5,8,11,14,17 - sel acide sodium eicosapentaénique, >=99% (GC capillaire)
Brand: SIGMA-ALDRICH
SKU: E6627-25MG
Price: 413.28 USD

Code: E6627-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:•to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models&...

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$413.28 25MG

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Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:•to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models•to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release•to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice

Biochem/physiol Actions

5-Lipoxygenase inhibitor; reduces thromboxane A2 production.

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.

General description

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.

assay	≥99% (capillary GC)
biological source	synthetic (organic)
color	white to off-white
form	film or powder
Gene Information	human ... ALOX5(240)mouse ... ALOX5(11689)rat ... ALOX5(25290)
InChI key	TVEGTERCKGGVCJ-LIJGWLRISA-N
InChI	1S/C20H30O2.Na.H/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22;;/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22);;/b4-3-,7-6-,10-9-,13-12-,16-15-;;
Quality Level	200
shipped in	dry ice
SMILES string	[Na].CCC=C/CC=C/CC=C/CC=C/CC=C/CCCC(O)=O
solubility	methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.	−20°C

Safety Data Sheet for E6627-25MG
Certificat d'analyse Sigma

Cas Number

73167-03-0

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

cis-5,8,11,14,17 - sel acide sodium eicosapentaénique, >=99% (GC capillaire)

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