Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
5,6-dimethylxanthenone-4-acetic acid (DMXAA) has been used to induce type-I IFN signaling in a stimulator of interferon genes (STING) dependent manner. It has also been used to study STING-dependent signaling in the absence of infection.
Biochem/physiol Actions
DMXAA is an apoptosis inducer; anti-vascular.
Features and Benefits
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General description
5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a flavone acetic acid derivative. It acts as a vascular disrupting agent (VDA), which damages tumor vasculature and stimulates an anti-tumor immune response. It stimulates hemorrhagic necrosis.
Packaging
5, 25 mg in glass bottle
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