A-317491 hydrate de sel de sodium, > = 98 %( HPLC), poudre

Name: A-317491 hydrate de sel de sodium, > = 98 %( HPLC), poudre
Brand: SIGMA-ALDRICH
SKU: A2979-5MG
Price: 265.20 USD

Code: A2979-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

A-317491 sodium salt hydrate has been used to block the P2X3 receptor. It has also been used to block the increased membrane conductance.

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Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
A-317491 sodium salt hydrate has been used to block the P2X3 receptor. It has also been used to block the increased membrane conductance.
Biochem/physiol Actions
A-317491 helps to decrease neuropathic and inflammatory pain by inhibiting the P2X3 receptor-mediated Ca²⁺influx.
Novel P2X₃ and P2X_2/3 receptor antagonist
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Legal Information
Subject to U.S. Patent No. 6,831,193. Sold under license from Abbott Laboratories
Packaging
5, 25 mg in glass bottle

assay ≥98% (HPLC)
color white to beige
form powder
InChI key VEMCGHRDAPMXLI-VYEUTZPBSA-N
InChI 1S/C33H27NO8.Na.H2O.H/c35-30(25-17-27(32(38)39)28(33(40)41)18-26(25)31(36)37)34(29-15-7-10-21-9-4-5-14-24(21)29)19-20-8-6-13-23(16-20)42-22-11-2-1-3-12-22;;;/h1-6,8-9,11-14,16-18,29H,7,10,15,19H2,(H,36,37)(H,38,39)(H,40,41);;1H2;/t29-;;;/m0.../s1
originator Abbott
Quality Level 100
SMILES string [Na].[H]O[H].OC(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(=O)N(Cc2cccc(Oc3ccccc3)c2)[C@H]4CCCc5ccccc45
solubility H₂O: 15 mg/mL, clear

Fiche de données de sécurité
Safety Data Sheet for A2979-5MG
Certificat d'analyse
Certificat d'analyse Sigma

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Cas Number 475205-49-3

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

A-317491 hydrate de sel de sodium, > = 98 %( HPLC), poudre

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assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	VEMCGHRDAPMXLI-VYEUTZPBSA-N
InChI	1S/C33H27NO8.Na.H2O.H/c35-30(25-17-27(32(38)39)28(33(40)41)18-26(25)31(36)37)34(29-15-7-10-21-9-4-5-14-24(21)29)19-20-8-6-13-23(16-20)42-22-11-2-1-3-12-22;;;/h1-6,8-9,11-14,16-18,29H,7,10,15,19H2,(H,36,37)(H,38,39)(H,40,41);;1H2;/t29-;;;/m0.../s1
originator	Abbott
Quality Level	100
SMILES string	[Na].[H]O[H].OC(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(=O)N(Cc2cccc(Oc3ccccc3)c2)[C@H]4CCCc5ccccc45
solubility	H₂O: 15 mg/mL, clear