Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Discoidin domain receptor I (DDR1) plays important roles in several cancers. In renal cancer cells, DDR1 promotes epithelial to mesenchymal transition. It also increases invasion and metastasis of gastric cancer through epithelial-mesenchymal transition.

Disclaimer

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General description

Discoidin domain receptor I (DDR1) is a receptor tyrosine kinase (RTK)/collagen-activated tyrosine kinase, that is located on human chromosome 6p21.

Immunogen

The antiserum was produced against synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr513.Immunogen Range: 479-528

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.