Monoclonal anti-sh3d19

Not available outside of the UK & Ireland.

Biochem/physiol Actions

SH3 domain containing 19 (SH3D19) inhibits processes induced by Ras oncoprotein. It binds to a protein called EEN (extra eleven-nineteen leukemia fusion gene protein), part of the endophilin family, and modulates the activity of ADAMs (a disintegrin and metalloproteases).

General description

SH3 domain containing 19 (SH3D19) is a cytoplasmic protein and the gene encoding it is localized on human chromosome 4q31.3.

Immunogen

SH3D19 (NP_001009555, 94 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequencePVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLI

Legal Information

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Physical form

Solution in phosphate buffered saline, pH 7.4